Head and Neck Carcinoma Clinical Trials & Research at St. Joseph Health Medical Group

Head and neck cancers start in the tissues and organs of the head and neck and include cancers of the larynx (voice box), throat, lips, mouth, nose, and salivary glands. Most head and neck cancers are squamous cell carcinomas and begin in the moist tissues that line the mouth, nose and throat. Tobacco use, heavy alcohol use, and infection with the human papillomavirus (HPV) increase your risk of head and neck cancer.

St. Joseph Health Medical Group is currently enrolling patients for the following head and neck carcinoma clinical trial:

A randomized phase III study of pembrolizumab given concomitantly with chemoradiation and as maintenance therapy versus chemoradiation alone in subjects with locally advanced head and neck squamous cell carcinoma (KEYNOTE-412)

  • Study name: KEYNOTE-412.
  • For patients with newly diagnosed, locally advanced head or neck cancer.
  • Patients are randomized to treatment arms in a 1:1 ratio: Pembrolizumab (Keytruda) or placebo plus chemoradiation.
  • Main study doctor (Principal Investigator): Ian Anderson, MD.
  • For more information, please contact the lead coordinator, Tracy Foster, at (707) 521-3836 or Tracy.Foster@stjoe.org.

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