Breast Cancer Clinical Trials & Research at Providence Medical Group

In the U.S., breast cancer is the second most common cancer in women after skin cancer. It can occur in both men and women. The most common type of breast cancer is ductal carcinoma, which begins in the cells of the ducts. Breast cancer can also begin in the cells of the lobules and in other tissues in the breast. Invasive breast cancer is breast cancer that has spread from where it began in the ducts or lobules to surrounding tissue.

Providence Medical Group is currently enrolling patients for the following breast cancer clinical trials:

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer (MA.39 TAILOR RT)

Treatment agent: Radiotherapy
Physician: Michael N. Corradetti, MD
Study Coordinator: Beatrice Becker // beatrice.becker@providence.org // 707-932-5164
Study Resources: https://clinicaltrials.gov/study/NCT03488693
Sponsor: National Cancer Institute (NCI) / Canadian Cancer Trials Group
Location: Providence Queen of the Valley Medical Center, Napa, CA

Sermonix SMX-22-002 ELAINE 3

Treatment agent: Lasofoxifene + abemaciclib vs fulvestrant + abemaciclib
Physician: Jarrod Holmes, MD
Study Coordinator: Camille Shaffer // camille.shaffer@stjoe.org // 707-521-3830
Study Resources: Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation - Full Text View - ClinicalTrials.gov
Sponsor: Sermonix Pharmaceuticals Inc.
Location: Providence Cancer Center, Santa Rosa, CA

Study for participants with Stave IV advanced/ metastatic Hormone Receptor positive, HER2 negative breast cancer (Capitello 292)

Treatment agent: Capiversitib + CDK4/6 inhibitor + Fulvestrant
Physician: Dr Jarrod Holmes
Study Coordinator: Camille Shaffer // camille.shaffer@stjoe.org // 707-521-3830
Study Resources: Study Details | Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292) | ClinicalTrials.gov
Sponsor: Capitello
Location: Providence Cancer Center, Santa Rosa, CA

Neo-adjuvant and adjuvant ( treatment study for participants with triple negative or hormone receptor low or HER2 negative breast cancer (Tropion Breast 04)

Treatment agent: Dato-DXd and Durvalumab
Physician: Dr Jarrod Holmes
Study Coordinator: Camille Shaffer // camille.shaffer@stjoe.org // 707-521-3830
Study Resources: Study Details | A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer | ClinicalTrials.gov
Sponsor: Astra Zeneca
Location: Providence Cancer Center, Santa Rosa, CA